Advancing Symptom Science Through Symptom Cluster Research: Expert Panel Proceedings and Recommendations

Advancing Symptom Science Through Use of Common Data Elements.

BACKGROUND Use of common data elements (CDEs), conceptually defined as variables that are operationalized and measured in identical ways across studies, enables comparison of data across studies in ways that would otherwise be impossible. Although healthcare researchers are increasingly using CDEs, there has been little systematic use of CDEs for symptom science. CDEs are especially important i...

Symptom cluster research: conceptual, design, measurement, and analysis issues.

Cancer patients may experience multiple concurrent symptoms caused by the cancer, cancer treatment, or their combination. The complex relationships between and among symptoms, as well as the clinical antecedents and consequences, have not been well described. This paper examines the literature on cancer symptom clusters focusing on the conceptualization, design, measurement, and analytic issues...

Noradrenergic symptom cluster in depression

Symptom clusters: the new frontier in symptom management research.

The majority of clinical studies on pain, fatigue, and depression associated with cancer are focused on one symptom. Although this approach has led to some advances in our understanding of a particular symptom, patients rarely present with a single symptom. Therefore, even though research focused on single symptoms needs to continue, it is imperative that symptom management research begins to f...

Measures and Methods for Symptom and Symptom Cluster Assessment in Adolescents and Young Adults with Cancer.

OBJECTIVES To provide an overview of resources for measuring symptoms and symptom clusters in adolescents and young adults (AYAs) with cancer and to examine methodological strategies for evaluating symptom clusters. DATA SOURCES Published research articles and clinical experience. CONCLUSION Limited research has addressed symptoms and symptom clusters in AYAs with cancer. Reliable, valid, a...